Pre and Post-Treatment Effects: Estimation of Serum Testosterone and Lipid Peroxidation Levels on Moringa olifera Extract Induced Cadmium Exposed Rats
Autor: | Pratik Kumar Chatterjee, Nayanatara Arun Kumar, Rashmi Kaup Shiva, Sneha B Shetty, Kunal, Mangalore Ramesh Bhat, Vinodini Nithyananda madom Anantharaya, Suman V. Budihal |
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Rok vydání: | 2017 |
Předmět: |
0301 basic medicine
Pharmacology Cadmium business.industry chemistry.chemical_element Physiology medicine.disease medicine.disease_cause Male infertility Lipid peroxidation Moringa 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology chemistry Biochemistry Drug Discovery Toxicity medicine Prospective cohort study business Oxidative stress Testosterone |
Zdroj: | Pharmacognosy Journal. 9:846-849 |
ISSN: | 0975-3575 |
DOI: | 10.5530/pj.2017.6.132 |
Popis: | Background: Cadmium (Cd), is a toxic metal which affects various organs including testis. It produces oxidative stress leading to male infertility. Moringa tree, is a natural plant with a great therapeutic value and hence it is found to be effective both in prevention and treatment of various conditions including reducing toxicity of hazardous materials. The aim of the present study was to examine the effects of Pre-and Post-treatment with Moringa oliefera leaf extract (MoE) on testis in cadmium exposed rats. Materials and Methods: The present study was conducted at the Department of Physiology, Kasturba Medical College (KMC), Mangalore, Manipal University (MU), Karnataka, India, between (2011-2013). This prospective study consisted a total of 30 rats. These were divided into 5 groups with group I being the control. Data were presented as mean ±SD. student’s t test was used as statistical tool, p |
Databáze: | OpenAIRE |
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