Effects of multivitamin, multimineral and phytonutrient supplementation on selected nutrient levels in blood and heart health risk factors in Russian population (831.4)
| Autor: | Vladimir V Bessonov, Alexandra Golubeva, Valentina Kazlova, Yumei Lin, T B Sentsova, Ksenia Selezneva, Victor A. Tutelyan, Vasily Isakov |
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| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Homocysteine Vitamin C business.industry Blood lipids Placebo Biochemistry chemistry.chemical_compound Red blood cell Endocrinology medicine.anatomical_structure chemistry Internal medicine Environmental health Genetics medicine Uric acid Multivitamin business Quercetin Molecular Biology Biotechnology |
| Zdroj: | The FASEB Journal. 28 |
| ISSN: | 1530-6860 0892-6638 |
| DOI: | 10.1096/fasebj.28.1_supplement.831.4 |
| Popis: | The primary objective of this exploratory study was to evaluate the effect of a multivitamin multimineral with phytonutrient supplement on heart health risk factors. One hundred twenty healthy adults (40-70 y) were recruited in this 8-week randomized double blind placebo control study. B-carotene, a-tocopherol, vitamin C, red blood cell (RBC) folate, B6, B12, Zn, Se content in blood were measured on Day 1, 28 and 56 and quercetin was measured on Day 1 and 56. Heart health risk factors such as homocysteine (Hcy), high-sensitivity C-reactive protein (hs-CRP), oxidized LDL (ox-LDL), gamma-glutamyl transferase (GGT), uric acid and blood lipid profile were monitored on Day 1 and 56. Results showed that supplementation significantly improved quercetin (p=0.0047), vitamin C (p=0.0011), RBC folate (p=0.0027) and B6 (p=0.0012) status after 8 weeks of consumption. A greater decrease of Hcy (p=0.0314), GGT (p=0.0545) and uric acid (p=0.1683) was also observed. However, a lesser degree of increase of hs-CRP (p=0.2511... |
| Databáze: | OpenAIRE |
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