Abstract TP90: Computed Tomography Perfusion Mismatch is Stable Over Time From Onset After Stroke Due to Underestimation of Core Infarct in Late Time Window
| Autor: | Johannes Pulst-Korenberg, John H. Woo, Steven R. Messé, Daniel Cristancho, James E. Siegler, Lindsay Raab, Andrew Olsen, Brett Cucchiara, Jon Rosenberg |
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| Rok vydání: | 2019 |
| Předmět: |
Advanced and Specialized Nursing
Core (anatomy) Computed tomography perfusion medicine.diagnostic_test business.industry Perfusion scanning Computed tomography medicine.disease Time windows Occlusion medicine Neurology (clinical) Cardiology and Cardiovascular Medicine business Nuclear medicine Stroke Large vessel occlusion |
| Zdroj: | Stroke. 50 |
| ISSN: | 1524-4628 0039-2499 |
| Popis: | Background: Automated computed tomography perfusion (CTP) imaging is proven effective at selecting patients with acute large vessel occlusion (LVO) for endovascular intervention in the extended time window (>6 hours after last known normal [LKN]). However, there are limited data on the likelihood of identifying core infarct-penumbral mismatch in the late time window. Hypothesis: Automated CTP mismatch ratios (Time-to-maximum residue function [T max ] >6s: relative cerebral blood flow [rCBF] Methods: We reviewed a retrospective registry of consecutive patients with LVO who underwent CTP within 24h of LKN at 3 academic hospitals between 06/2017 - 12/2017. Unenhanced CT and CTP parameters were compared between patients who presented within 12h of LKN versus 12-24h of LKN. Results: Among 60 included patients, the median age was 78 years (IQR 64-84), 36 (60.0%) were female, and 39 (65.0%) underwent thrombectomy. Patients who presented at 12-24h had poorer ASPECTS scores than patients who presented Conclusions: As time progresses in acute anterior LVO, the unenhanced CT may be more sensitive than rCBFFigure caption: ASPECTS and rCBF |
| Databáze: | OpenAIRE |
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