Control of tryptophan oxygenase and formamidase activity in the gerbil
| Autor: | John M. Franz, Kenneth L. Baughman |
|---|---|
| Rok vydání: | 1971 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty animal diseases Tryptophan Tryptophan oxygenase activity Cycloheximide Biology Gerbil Biochemistry chemistry.chemical_compound Endocrinology Enzyme chemistry Internal medicine Tryptophan Oxygenase parasitic diseases medicine Formamidase activity sense organs Glucocorticoid medicine.drug |
| Zdroj: | International Journal of Biochemistry. 2:201-211 |
| ISSN: | 0020-711X |
| DOI: | 10.1016/0020-711x(71)90213-8 |
| Popis: | 1. 1. Mongolian gerbil tryptophan oxygenase activity is essentially undetectable in the untreated animal, is not increased by stress or glucocorticoid administration, but rises significantly following injection of pharmacological doses of tryptophan. 2. 2. Increased apoenzyme conjugation and inhibition by actinomycin D and cycloheximide characterize the tryptophan-induced increase. 3. 3. Gerbil formamidase activity is significant in the untreated animal and the level is not altered by stress, glucocorticoids, or tryptophan. Formamidase activity develops more slowly in the perinatal gerbil than in the young rat. 4. 4. Important differences between the rat and gerbil with regard to these enzymes are emphasized. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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