A Dimensional Approach to Neurocognition in Psychopathology

Autor: Lipsitz, Orly, Ruocco, Anthony Charles, Carnovale, Michael
Rok vydání: 2023
Předmět:
DOI: 10.17605/osf.io/hfj3m
Popis: Replicated evidence has demonstrated that individuals with psychiatric disorders often experience neurocognitive deficits; However, to date, disorder-specific relationships with neurocognition have not been sufficiently identified. One limitation of extant research may be the reliance on defining psychiatric disorders as binary entities based on the Diagnostic and Statistical Manual for Mental Disorders (DSM). The DSM is limited by poor inter-rater reliability, within-disorder heterogeneity, high levels of comorbidity, and arbitrary thresholds of “illness”. Empirically-based approaches for assessing psychopathology using hierarchical dimensional structures, such as the Hierarchical Taxonomy of Psychopathology (HiTOP), aim to address the limitations of the DSM by organizing psychopathology from general to specific dimensions. Adopting a HiTOP approach for measuring psychopathology may better elucidate shared and unique relationships between psychopathology and neurocognition. In this remote, unsupervised study, 1000 adults with mental health concerns will complete the SPECTRA: Indices of Psychopathology (a dimensional assessment of psychopathology) and a neurocognitive battery. Data will be analyzed using structural equation modeling to evaluate the relationship between general and specific factors of psychopathology and neurocognition. Findings from this study may aid in identifying potential general or specific neurocognitive treatment targets.
Databáze: OpenAIRE