| Autor: |
Daniele Marciano, Rachel Haring, Eliahu Heldman, Einat Sadot, Z. Pittel, Abraham Fisher, Yishai Karton, David Gurwitz, Haim Meshulam, Irit Ginzburg, Rachel Brandeis, Leah Behar, Jacob Barg |
| Rok vydání: |
1997 |
| Předmět: |
|
| Zdroj: |
Alzheimer Disease ISBN: 9781461286608 |
| DOI: |
10.1007/978-1-4612-4116-4_47 |
| Popis: |
Restoration of ACh levels or replacement with an M1 (or m1) muscarinic agonist may be effective in treating at least some of the cognitive symptoms in Alzheimer’s disease (AD), (see Court and Perry, 1991; Fisher and Barak, 1994). Treatment approaches for AD have to address abnormalities occurring also along various signal transduction pathways (Harrison et al., 1991). Novel activities associated with m1 muscarinic receptors (m1 mAChR) indicate that m1 agonists may also activate hypofunctional signalling pathways in AD (Fisher and Barak, 1994; Gurwitz et al., 1994). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
