COVID-19 Vaccine Acceptance in Nigeria: A Rapid Systematic Review and Meta-Analysis

Autor: Victory Chizaram Nnaemeka, Nnenna Audrey Okafor, Oluwatosin Qawiyy Orababar, Ruth Anikwe, Reuben Ogba Onwe, Nneka Patricia Uzochukwu, Thomas Sambo Tsiterimam, Nkiru Nenye Nwokoye, Anthony Chibuogwu Ike
Rok vydání: 2023
Popis: Widespread COVID-19 vaccination is essential to maintaining pandemic control. However, low- and lower-middle-income countries (LMICs) continue to face challenges to care due to unequal access and vaccine fear despite the introduction of safe and effective immunizations. This study aimed to collect information on Nigeria’s COVID-19 vaccine uptake rates and determinants. Science Direct, PubMed, Google Scholar, African Journal Online, Springer, and Hinari were all systematically searched through and completed in May 2022. Quality assessments of the listed studies were performed using the eight-item Joanna Briggs Institute Critical Appraisal tools for cross-sectional studies. In addition, we undertook a meta-analysis to calculate pooled acceptance rates with 95% confidence intervals (CI). Forty-two studies in total satisfied the inclusion criteria and were reviewed. A total of 24,533 respondents were studied. The total sample size of states in the Northern, Western and Southern parts of Nigeria are 3,206, 4,527 and 5,059, respectively, while 11,741 is the cumulative sample size of all the Nigeria-wide studies. The total COVID-19 vaccination acceptance rate among all the study groups was 52.4% (95% CI: 46.9-57.9%,I2= 100%), while the total estimated COVID-19 vaccination hesitancy rates was 47.81% (95% CI: 42.2 – 53.4%I2= 100%). In Nigeria-regions sub-group analyses, the Western region (58.90%, 95% CI: 47.12–70.27%) and Northern region (54.9%, 95% CI: 40.11%–69.4%) showed the highest rates of vaccine acceptance and vaccine hesitancy respectively. The COVID-19 vaccine acceptance rate was highest in 2020, with a pooled rate of 59.56% (46.34, 57.32%,I2= 98.7%). The acceptance rate in 2021 was only 48.48 (40.78%, 56.22%), while for the studies in 2022, it increased to 52.04% (95% CI: 35.7%, 68.15 %). The sensitization of local authorities and the dissemination of more detailed information about the COVID-19 vaccine and its safety, could significantly increase the country’s vaccination rate.
Databáze: OpenAIRE