A Dosage Response Equation for Androgen Assay by the Chick Comb Method
| Autor: | Emanuel Klempner, Robert T. Frank, Franklin Hollander |
|---|---|
| Rok vydání: | 1941 |
| Předmět: | |
| Zdroj: | Experimental Biology and Medicine. 46:1-5 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-46-11869p |
| Popis: | In previous reports on the relation between dosage of crystalline androsterone (A)† and mean comb weight (W) of white leghorn chicks, we described experiments involving 582 chicks in 5 monthly series. Each series consisted of 6 “gamma-groups” of chicks;1,2i.e., each bird received a total dose of 0, 10, 20, 30, 40 or 50γ androsterone in 0.35 cc of sesame oil, 0.05 cc being applied to the comb daily from the 3rd to the 9th day after hatching. The comb was excised and weighed on the 10th day.In the work now reported the number of series was increased to 10 (1439 chicks) over a period of 12 months, but in addition to W, A, Nm, and Nf, we recorded Bo and B. We also continued to run a control (zero γ) group of chicks with each series, as a measure of variations in spontaneous comb growth activity associated with season and batch of chicks. Using these combined data, we investigated graphically and statistically the desirability of applying to W for any series and sex a simple correction for mean comb weight of ... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|