STUDY OF THYROID HORMONE RECEPTORS EXPRESSION IN ABDOMINAL VISCERAL ADIPOCYTES OF OBESE VERSUS LEAN SUBJECTS

Autor: Hanan Mahmoud Ali, Mohammad Sobhi Hassan, Mohammad Hamed, Manal Abu-Shady, Aliaa Algarhi
Rok vydání: 2020
Předmět:
Zdroj: Ain Shams Medical Journal. 71:481-491
ISSN: 2735-3540
Popis: Background: Thyroid hormones are known to help in weight loss by stimulating metabolism, and they can help decrease cholesterol too. The activity of these hormones is regulated by chemicals called hormone receptors. Selective activation of these receptors may be able to effectively treat obesity, hypercholesterolemia; really a novel way of looking at obesity.Aim of work: To measure the expression levels of thyroid hormone receptors in adipocytes of obese patients versus leansubjects, pointing out the effect of obesity on thyroid receptors and that of thyroid on burning fat and in turn forming an idea about thyroid regulatory status. Patients and Methods: Case control study .Visceral adipose tissue samples will be provided from patients undergoing elective abdominal surgery. This study will be conducted on two groups: Group ob: comprises 20 obese subjects (BMI>30kg/m2) Group ln: comprises 20 lean subjects (BMI
Databáze: OpenAIRE