Isolation of an Anti-Thiamine Compound from Bergenia ciliata leaves of Sikkim Himalaya

Autor:	Tanaya Ghosh, Prasanta Kumar Mitra
Rok vydání:	2022
Předmět:	General Engineering food and beverages General Earth and Planetary Sciences human activities General Environmental Science
Zdroj:	Saudi Journal of Biomedical Research. 7:41-44
ISSN:	2518-3222 2518-3214
DOI:	10.36348/sjbr.2022.v07i01.006
Popis:	Recently we have shown that Bergenia ciliate (B. ciliate, Family- Saxifragacae) leaves of the period July – August had maximum in vitro anti thiamine effect. Aim of the present work was, to isolate anti thiamine compound from the leaves of B. ciliate. From the local market B. ciliate leaves were collected during July – August and identified by the taxonomist. Solvent extraction and acid hydrolysis were done followed by solvent treatment, chromatographic experiments and crystallization. A compound was crystallized. In vitro anti thiamine activity of the isolated compound was checked by standard method. Results revealed that 100 mg of the isolated compound could inactivate 29.5 mg of thiamine hydrochloride in in vitro experiment.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0b5aac3bd8675ce995c08a5e414c31f2 https://doi.org/10.36348/sjbr.2022.v07i01.006 Zobrazit plný text záznamu