Reduction in skin test reactions to inhaled allergens during a 12 weeks stay in the alpine climate
| Autor: | Egidius A.H. Panis, Bernardus Speelberg, Jan G. R. De Monchy |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
House dust mite
integumentary system biology business.industry Plant Science Skin test biology.organism_classification medicine.disease medicine.disease_cause Vial Obstructive lung disease respiratory tract diseases chemistry.chemical_compound Allergen chemistry Anesthesia Immunology medicine Potency business Ecology Evolution Behavior and Systematics Histamine Asthma |
| Zdroj: | Grana. 30:155-160 |
| ISSN: | 1651-2049 0017-3134 |
| DOI: | 10.1080/00173139109427791 |
| Popis: | Fiftyfour allergic patients with bronchial asthma or obstructive lung disease were investigated at admission and discharge after a 3 months hospitalization period in the alpine valley Davos. An intracutaneous skin test procedure was carried out with 16 common inhalant allergens. Histamine 0.01 mg/ml was used as a positive control and a phosphate buffered saline with 0.03% HSA and 0.5% phenol were used as negative controls. A liophylized control for house dust mite was used for every patient on admission and discharge, in order to control loss of allergen potency of the vial. Furthermore, an additional freshly prepared vial of house dust mite allergen was analyzed after it was opened and stored at 4°C after 3 months. The wheal and flare reactions were calculated separately for the early reaction (at 15 minutes) and the late reaction (at 6 hours). The sum of wheal/histamine index and fare/histamine index were calculated for the early phase reactions and analyzed according two-tailed paired student'... |
| Databáze: | OpenAIRE |
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