| Autor: |
Paul L. Gourley, Darryl Y. Sasaki, Steven K. Skirboll, Mark S. Curry, Susan C. Follstaedt, Jimmy D. Cox |
| Rok vydání: |
2001 |
| Předmět: |
|
| Zdroj: |
SPIE Proceedings. |
| ISSN: |
0277-786X |
| DOI: |
10.1117/12.427966 |
| Popis: |
The development of microsystems that merge biological materials with microfabricated structures is highly dependent on the successful interfacial interactions between these innately incompatible materials. Surface passivation of semiconductor and glass surfaces with thin organic films can attenuate the adhesion of proteins and cells that lead to biofilm formation and biofouling of fluidic structures. We have examined the adhesion of glial cells and serum albumin proteins to microfabricated glass and semiconductor surfaces coated with self-assembled monolayers of octadecyltrimethoxysilane and N-(triethoxysilylpropyl)-O- polyethylene oxide urethane, to evaluate the biocompatibility and surface passivation those coatings provide. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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