Synthesis of (+)/(−) pentenomycins via Me2AlCl induced cascade reaction

Autor:	Bejugam Santhosh Kumar, Batchu Venkateswara Rao, Girija Prasad Mishra
Rok vydání:	2013
Předmět:	chemistry.chemical_compound Cascade reaction Chemistry Stereochemistry Organic Chemistry Drug Discovery Ribose Mannose Biochemistry
Zdroj:	Tetrahedron Letters. 54:2845-2848
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2013.03.092
Popis:	An efficient approach for the synthesis of (+) pentenomycin and (−) pentenomycin from d -ribose and d -mannose, respectively, is described using Tebbe olefination of lactones 9 and 7 followed by Me 2 AlCl induced disfavoured 5 -(enol-endo)-exo-trig cyclization.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0b364a4fb491c1c615883b88bffa3413 https://doi.org/10.1016/j.tetlet.2013.03.092 Zobrazit plný text záznamu Full Text from ScienceDirect