Prevalência da infecção pelo vírus da hepatite B em um município do interior do estado do Acre, Amazônia Ocidental, Brasil

Autor: Rita do Socorro Uchôa da Silva, Francileide Ferreira da Rocha, Sueli Santiago da Silva, Maria Lucimar Almeida da Costa, Glivia Maria do Nascimento Torres, Isadora Oliveira Morais, Paula Alessandra Martins da Silva, Renata Souza, Irenilce Souza de Matos, Danielly Moreira Gonçalves
Rok vydání: 2017
Předmět:
Zdroj: Revista Pan-Amazônica de Saúde. 8:19-26
ISSN: 2176-6223
DOI: 10.5123/s2176-62232017000300003
Popis: OBJECTIVE: To estimate the prevalence of hepatitis B virus (HBV) in individuals living in Porto Acre municipality, Acre State, Western Brazilian Amazon. MATERIALS AND METHODS: Cross-sectional study carried out with residents of Porto Acre who had attended the basic health units in 2012 were invited to answer a standardized questionnaire and to donate venous blood. As screening, immunochromatographic rapid test (IRT) for hepatitis B (HBsAg) was used, and from whom that was reagent to the IRT, serological tests (HBsAg and total anti-HBc) were performed. The HBeAg, anti-HBe and total anti-HD markers were used exclusively in the samples whose HBsAg remained serologically reagent. RESULTS: It was included 646 individuals (4.7% of the population), 57.6% of the female gender. Seventeen individuals (2.6%) were reagent to the IRT for HBsAg and of which in 82.3% (14/17) presented serological confirmation. Total anti-HBc was reactive in 31.9% (206/646) of the subjects, of which 2.2% (14/646) had current HBV and 29.7% (192/646) only evidence of previous infection. Of the 184 (28.5%) children and adolescents included in this study, 9.2% (17/184) had prior contact with HBV. The abusive alcohol intake is correlated to HBsAg and total anti-HBc reactivity, whereas older age, male gender, previous surgeries, and the presence of tattoos were related exclusively to total anti-HBc higher reactivity. CONCLUSION: HBsAg seroprevalence was 2.2% and total anti-HBc approximately 32.0%. There was detection of total anti-HBc in 9.2% of the children and adolescents included in the study, evidencing early contact with HBV in this population.
Databáze: OpenAIRE