| Autor: |
Francine Carla Cadoná, Aline Ferreira Ourique, Fernanda Reis Favarin, David Frederick Bodenstein, Alencar Kolinski Machado, Carina Rossoni |
| Rok vydání: |
2020 |
| Předmět: |
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| DOI: |
10.1016/b978-0-12-819666-3.00002-x |
| Popis: |
Cancer treatment is considered a huge challenge to the science. Cancer cells frequently present resistance to chemotherapy and have fast proliferation. In this sense, several functional foods have been studied for anticancer purposes since they present a chemical matrix rich in bioactive molecules. Some of these molecules show important antitumor proprieties by increasing chemotherapy response and decreasing cancer cell proliferation. However, bioactive molecules stability and tissue-specific delivery are still challenging in the natural product field. In this context, there are many investigations looking forward to develop methods to increase bioavailability and/or to avoid degradation. Some of these researches propose nanoformulations as delivery cargoes of food bioactive molecules and nutraceuticals that could achieve these objectives. Polymeric nanoparticles have been especially used in oncology to easily transport and deliver antitumor agents. Therefore polymeric nanoparticles as delivery cargoes of food bioactives and nutraceuticals are great alternatives to reveal potent anticancer agents that could be able to improve chemotherapy treatment, decrease cancer cells resistance, and reduce side effects. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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