RESPONSIVENESS OF STATE AND RESPONSE ENTROPY AND ALGESIOMETRY DURING INTRAVENOUS FENTANYL ADMINISTRATION: A COMPARISON BETWEEN MALE AND FEMALE PATIENTS
| Autor: | Kalyani J Paighan, Nirmala Jonnavithula, Reetham Muddamalla, Achutuni Jyothi, Padmaja Durga |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Asian Journal of Pharmaceutical and Clinical Research. :51-54 |
| ISSN: | 2455-3891 0974-2441 |
| Popis: | Aims and Objectives: The aim of the study was to assess the gender difference in response to fentanyl on the entropy and algesiometry and to compare hemodynamic difference in between the gender. Methods: It was a prospective observational study carried out in a group of 100 patients, of which 50 were males and 50 females. In both the groups, baseline entropy (response entropy [RE] and state entropy [SE]) and algesiometry values were recorded, 2 mic/kg of fentanyl was administered, and entropy values were recorded for 5 min and another algesiometry reading was taken at the end of 5 min. Results: Both the groups were found to be comparable age and weight (p0.05). There was no significant difference in entropy values among males and females before and after fentanyl administration. Females had significantly (p=0.033) lower pain threshold and a statistically significant increase in pain threshold as compared to males after fentanyl administration (p=0.012). Conclusion: We conclude that fentanyl administration has not influenced the entropy values based on gender and females had an initial low pain threshold and a greater increase in pain threshold after fentanyl administration. |
| Databáze: | OpenAIRE |
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