Study of the Interaction of Concanavalin A with Staphylococcal Teichoic Acids

Autor: W. J. Reeder, R. D. Ekstedt
Rok vydání: 1971
Předmět:
Zdroj: The Journal of Immunology. 106:334-340
ISSN: 1550-6606
0022-1767
Popis: The interaction of Concanavalin A with teichoic acids from S. aureus and S. epieermidis has been studied by gel diffusion and precipitation in a fluid system. It was found that Concanavalin A reacted with alpha-glucosylated but not with beta-glucosylated teichoic acids from S. epidermidis. It was similarly found that Concanavalin A reacted only with the alpha-linked N-acetylglucosamine teichoic acids from strains of S. aureus. These observations were substantiated by quantitative precipitin and hapten inhibition studies using specific antisera to the staphylococcal strains studied. The usefulness of the interaction of Concanavalin A with teichoic acids in studying the immunochemistry of these antigens was demonstrated.
Databáze: OpenAIRE