PULMONARY VASOREACTIVITY TESTING WITH ADENOSINE PREDICTS LONG TERM HEMODYNAMIC RESPONSE TO PROSTACYCLIN MONOTHERAPY, AND PROSTACYCLIN AND PHOSPHODIESTERASE-5 INHIBITOR COMBINATION THERAPY IN PULMONARY ARTERIAL HYPERTENSION
Autor: | Jonathan D. Rich, Ramsey M. Wehbe, Stuart Rich |
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Rok vydání: | 2018 |
Předmět: |
medicine.medical_specialty
genetic structures medicine.drug_mechanism_of_action Combination therapy business.industry Haemodynamic response Low dose Prostacyclin behavioral disciplines and activities Adenosine Calcium channel blocker therapy Internal medicine mental disorders medicine Cardiology In patient Cardiology and Cardiovascular Medicine business Phosphodiesterase 5 inhibitor medicine.drug |
Zdroj: | Journal of the American College of Cardiology. 71:A1951 |
ISSN: | 0735-1097 |
DOI: | 10.1016/s0735-1097(18)32492-6 |
Popis: | Pulmonary vasoreactivity testing (PVT) with low dose adenosine predicts the clinical response to calcium channel blocker therapy in patients with pulmonary arterial hypertension (PAH). While higher dose adenosine PVT predicts the hemodynamic response to prostacyclin therapy (PGI2) after 1 year, it |
Databáze: | OpenAIRE |
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