Studies on the enantioselective synthesis of α-amino acids via asymmetric phase-transfer catalysis
| Autor: | T. R. Lowdon, P. G. Wainwright, J. A. Peterson, Barry Lygo, John Crosby |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
chemistry.chemical_classification
biology organic chemicals Organic Chemistry Enantioselective synthesis Cinchona Alkylation biology.organism_classification Biochemistry Amino acid Catalysis chemistry.chemical_compound chemistry Phase (matter) Drug Discovery Organic chemistry heterocyclic compounds Ammonium |
| Zdroj: | Tetrahedron. 57:2403-2409 |
| ISSN: | 0040-4020 |
| DOI: | 10.1016/s0040-4020(01)00094-1 |
| Popis: | In this paper, we describe investigations into the use of cinchona alkaloid-derived quaternary ammonium phase-transfer catalysts for the asymmetric alkylation of a benzophenone-derived glycine-imine. Utility of this process is demonstrated by the enantioselective synthesis of a range of α-amino acid esters. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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