Three-Dimensional Analysis of Round Window Membrane in the Chinchilla Model with Acute Otitis Media Induced with Streptococcus Pneumoniae 7F
| Autor: | Mehmet Kazım Börkü, Sebahattin Cureoglu, Hasan Albasan, Nevra Keskin Yılmaz, Michael M. Paparella |
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| Rok vydání: | 2021 |
| Předmět: |
Chinchilla
Streptococcus pneumoniae 7F Three dimensional analysis Round window 010504 meteorology & atmospheric sciences biology business.industry Acute otitis media medicine.medical_treatment Inner Ear Diseases medicine.disease_cause 01 natural sciences medicine.anatomical_structure biology.animal Streptococcus pneumoniae Medicine sense organs business Nuclear medicine Saline 0105 earth and related environmental sciences |
| Zdroj: | Turkish Archives of Otorhinolaryngology. 59:43-48 |
| ISSN: | 1303-6289 0304-4793 |
| Popis: | Objective The purpose of this study was to investigate the morphological changes of round window membrane (RWM) in chinchillas with Streptococcus pneumoniae (S. pneumoniae) serotype 7F induced acute otitis media (AOM) by two dimensional (2D) and three dimensional (3D) measurements. Methods Temporal bone specimens taken from 12 chinchillas were divided into two groups. The control group consisted of healthy animals that were injected with intrabullar saline. The subjects in the experimental group were induced with AOM by intrabullar injection of S. pneumoniae 7F. The 2D and 3D measurements of RWM were compared between the groups. Results Dramatic changes were noted in the RWM of the experimental group compared to the control group. The thickness [mean ± standard deviation (SD)] of the RWM was significantly (p |
| Databáze: | OpenAIRE |
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