| Popis: |
The effects of magnesium pemoline, tricyanoaminopropene, and d-amphetamine on the acquisition of a discriminated avoidance response were compared in 30-, 50-, and 100-day-old naive rats. The rats were placed in an automated shuttlebox immediately after drug treatment. The number of avoidance responses in a series of 100 trials was measured. Ten days after the initial acquisition session, the rats were retrained on the same task. The 30-day group was inferior to the 50- and 100-day groups in the training session, but no differences occurred in retraining. The drug-treated groups showed improved performance in the initial training session but were not different from the controls in the retraining session. No Drug by Age interaction was significant. |
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