INVASIVE PNEUMOCOCCAL INFECTIONS IN CHILDREN INFECTED WITH HIV-1 ARE NOT ASSOCIATED WITH SPLENIC DYSFUNCTION. † 976

Autor: Howard A. Pearson, B. Joyce Simpson, Christine Holtkamp, Warren A. Andiman
Rok vydání: 1996
Předmět:
Zdroj: Pediatric Research. 39:165-165
ISSN: 1530-0447
0031-3998
DOI: 10.1203/00006450-199604001-00998
Popis: Children infected with human immunodeficiency virus type 1 (HIV) are more likely to acquire infections with encapsulated bacterial pathogens of childhood than their non-HIV-infected peers. It has been shown thatStreptococcus pneumoniae (pneumococcus) accounts for 35% of the bacterial isolates from blood and cerebrospinal fluid in this group of children. We wished to learn what proportion (if any) of the incidence of community-acquired, invasive pneumococcal disease in HIV-infected children could be attributed to splenic dysfunction, as measured quantitatively by enumerating the number of pocked red blood cells in peripheral blood (Pearsonet al Pediatrics 1985; 76:392).
Databáze: OpenAIRE