Assessment of a sheep animal model to optimise photodynamic therapy in the oesophagus
| Autor: | A. Radu, Georges Wagnières, Raphaelle Pilloud, Francois Borle, Ramiro Conde, Hubert van den Bergh, Snezana Andrejevic-Blant, Jean-Pierre Ballini, Matthieu Zellweger, Thomas M. Glanzmann, Philippe Monnier, Yves Jaquet |
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| Rok vydání: | 2009 |
| Předmět: |
Oncology
Pathology medicine.medical_specialty business.industry medicine.medical_treatment Cancer Photodynamic therapy Dermatology medicine.disease digestive system diseases chemistry.chemical_compound Animal model chemistry Internal medicine Chlorin polycyclic compounds medicine Adenocarcinoma Effective treatment heterocyclic compounds Surgery business |
| Zdroj: | Lasers in Surgery and Medicine. 41:643-652 |
| ISSN: | 0196-8092 |
| Popis: | Precursor lesions of oesophagus adenocarcinoma constitute a clinical dilemma. Photodynamic therapy (PDT) is an effective treatment for this indication, but it is difficult to optimise without an appropriate animal model. For this reason, we assessed the sheep model for PDT in the oesophagus with the photosensitiser meta-(tetra-hydroxyphenyl) chlorin (mTHPC). |
| Databáze: | OpenAIRE |
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