Endocytosed HIV-1 Envelope Glycoprotein Traffics to Rab14+Late Endosomes and Lysosomes to Regulate Surface Levels in T-Cell Lines
| Autor: | Huxley K. Hoffman, Rebekah S. Aguilar, Austin R. Clark, Nicholas S. Groves, Nairi Pezeshkian, Merissa M. Bruns, Schuyler B. van Engelenburg |
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| Rok vydání: | 2022 |
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| Zdroj: | Journal of Virology. 96 |
| ISSN: | 1098-5514 0022-538X |
| DOI: | 10.1128/jvi.00767-22 |
| Popis: | HIV-1 envelope glycoprotein (Env) evades immune neutralization through many mechanisms. One immune evasion strategy may result from the internalization of excess surface-exposed Env to prevent antibody-dependent cellular cytotoxicity or neutralization. |
| Databáze: | OpenAIRE |
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