Autor:	Valerio Berdini, Alessandra Topai, Nicolini Luca, Marcello Allegretti, M. Candida Cesta, Roberto Curti
Rok vydání:	2001
Předmět:	chemistry.chemical_compound Primary (chemistry) Aqueous solution chemistry Organic Chemistry Drug Discovery Ammonium formate Organic chemistry Stereoselectivity Methanol Biochemistry Reductive amination
Zdroj:	Tetrahedron Letters. 42:4257-4259
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(01)00663-3
Popis:	A palladium-catalysed reduction of ketones to primary amines by reaction with ammonium formate in aqueous methanol is described. The proposed method provides a one-pot synthesis of 3-endo-tropanamine in high yields and stereoselectivity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0a6791b3b43ebf972228b332a3e5213b https://doi.org/10.1016/s0040-4039(01)00663-3 Zobrazit plný text záznamu Full Text from ScienceDirect