A Liquid Formulation of a Long-acting Erythropoietin Conjugate

Autor:	Kwon Se Chang, Jung Sung Youb, Sung Min Bae, Min Young Kim, Lim Chang Ki, Dae Seong Im
Rok vydání:	2020
Předmět:	Chromatography Chemistry Biomedical Engineering Bioengineering Human serum albumin Applied Microbiology and Biotechnology High-performance liquid chromatography Long acting Erythropoietin In vivo medicine Mannitol Biotechnology medicine.drug Stabilizer (chemistry) Conjugate
Zdroj:	Biotechnology and Bioprocess Engineering. 25:117-125
ISSN:	1976-3816 1226-8372
DOI:	10.1007/s12257-019-0194-3
Popis:	Disclosed is a liquid formulation which allows long-acting EPO conjugates, that have improved in vivo duration and stability, to be stable when stored for a long period of time. It comprises a stabilizer composition characterized by buffer and mannitol. Being free of human serum albumin and other potential factors harmful to the body, the liquid formulation is free of concerns about viral infections and guarantees excellent storage stability to long-acting EPO conjugates.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0a3cf7d9674a85fc03cfb29f990ad725 https://doi.org/10.1007/s12257-019-0194-3 Zobrazit plný text záznamu Full text from SpringerLink