Antibacterial Screening of Endophytic Fungus Xylaria sp. derived from Andrographis paniculata (Sambiloto)
Autor: | Riga Riga, Mariam Ulfah, Suryelita Suryelita, Muh Ade Artasasta, Sri Benti Etika |
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Rok vydání: | 2021 |
Předmět: |
biology
Traditional medicine business.industry fungi Ethyl acetate food and beverages General Medicine Fungus biology.organism_classification Plant use of endophytic fungi in defense chemistry.chemical_compound chemistry Potato dextrose agar Medicine Fermentation Agar diffusion test Antibacterial activity business Andrographis paniculata |
Zdroj: | Open Access Macedonian Journal of Medical Sciences. 9:971-975 |
ISSN: | 1857-9655 |
Popis: | AIM: The purpose of this research is to evaluate the antibacterial activity of endophytic fungi derived from the flowers of Andrographis paniculata (Sambiloto). METHODS: The endophytic fungi were obtained following the dilution method with potato dextrose agar as media. Four isolates of fungi have been obtained and then fermented with rice media for 3 weeks. The fermented fungi were extracted with ethyl acetate (EtOAc) and evaporated to yield the EtOAc extract. All EtOAc extracts were evaluated for their antibacterial activity using agar diffusion method. RESULTS: The results indicated that the EtOAc extract from fungus RG-2 was the potential source of antibacterial compounds. Molecular identification showing fungus RG-2 was Xylaria sp. CONCLUSION: Further investigation of the antibacterial compounds produced by fungus Xylaria sp. derived from the flowers of A. paniculata will be performed in the future. To the best of our knowledge, endophytic fungal Xylaria sp. is firstly isolated from A. paniculata. |
Databáze: | OpenAIRE |
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