Conjugates of 3,4-dimethoxy-4-styrylnaphthalimide and bacteriochlorin for theranostics in photodynamic therapy
| Autor: | M. A. Grin, Andrey F. Mironov, Pavel A. Panchenko, Valentine G. Nenajdenko, Danil P. Zarezin, Olga A. Fedorova, Dmitriy A. Pritmov, Marina A. Zakharko |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Fluorophore
010405 organic chemistry Singlet oxygen medicine.medical_treatment Energy transfer Photodynamic therapy General Chemistry 010402 general chemistry Photochemistry 01 natural sciences 0104 chemical sciences Photoexcitation chemistry.chemical_compound chemistry medicine Photosensitizer Conjugate |
| Zdroj: | Russian Chemical Bulletin. 69:1169-1178 |
| ISSN: | 1573-9171 1066-5285 |
| DOI: | 10.1007/s11172-020-2885-5 |
| Popis: | New conjugates of fluorophore based on 3,4-dimethoxy-4-styryl-1,8-naphthalimide and photosensitizer bacteriochlorin e differing in the nature of spacer fragments were synthesized and their spectral-luminescent properties were studied. The conjugates efficiently generate singlet oxygen in solution, however, the emission of the naphthalimide fragment of the conjugates is quenched to varying degrees as a result of the photoexcitation energy transfer to bacteriochlorin. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink