Effect of experimental traumatic shock of varied severity and of propranolol on metabolic reaction of leukocytes

Autor: Lishmanov IuB, Zoloev Gk, Slepushkin Vd
Rok vydání: 1984
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 97:261-264
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf00800822
Popis: Intravenous injection of parathyroidine to intact rats in a dose of 2 Units/100 g bw provoked a hypotensive effect. The blockade of alpha-adrenoreceptors did not change the effect of parathyroid hormone. The stable analog of leu-enkephalin inhibited the parathyroidine-induced increase in cAMP level in the vascular wall with no influence on the hypotensive action of parathyroid hormone. Since the hypotensive action of parathyroidine was blocked with isoptin, it is concluded that parathyroid hormone primarily influences sodium-calcium metabolism in the vascular wall.
Databáze: OpenAIRE