Development of Off-On Switching 19F MRI Probes for Cathepsin K Activity Detection

Autor: Masafumi Minoshima, Yuki Konishi, Fuminori Sugihara, Kazuya Kikuchi, Kazuki Akazawa, Tatsuya Nakamura, Atsuya Okunishi
Rok vydání: 2021
Předmět:
Zdroj: Bulletin of the Chemical Society of Japan.
ISSN: 1348-0634
0009-2673
DOI: 10.1246/bcsj.20210099
Popis: Cathepsin K is a protease expressed in osteoclasts that degrades bone tissue, such as type I collagen fibers. Overexpression of cathepsin K is involved in osteoporosis, rheumatoid arthritis, and bo...
Databáze: OpenAIRE