Development of Off-On Switching 19F MRI Probes for Cathepsin K Activity Detection
Autor: | Masafumi Minoshima, Yuki Konishi, Fuminori Sugihara, Kazuya Kikuchi, Kazuki Akazawa, Tatsuya Nakamura, Atsuya Okunishi |
---|---|
Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Bulletin of the Chemical Society of Japan. |
ISSN: | 1348-0634 0009-2673 |
DOI: | 10.1246/bcsj.20210099 |
Popis: | Cathepsin K is a protease expressed in osteoclasts that degrades bone tissue, such as type I collagen fibers. Overexpression of cathepsin K is involved in osteoporosis, rheumatoid arthritis, and bo... |
Databáze: | OpenAIRE |
Externí odkaz: |