Co-crystal polymorphic control by nanodroplet and electrical confinement
| Autor: | Ahmad Ziaee, Barry Long, Bernardo Castro-Dominguez, Emmet J. O'Reilly, Kevin M. Ryan, Luis Padrela, Gavin Walker |
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| Rok vydání: | 2019 |
| Předmět: |
Materials science
Tandem technology industry and agriculture 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics 01 natural sciences Supercritical fluid 0104 chemical sciences Solvent Crystal Solvent evaporation Chemical engineering Metastability Nano General Materials Science 0210 nano-technology |
| Zdroj: | CrystEngComm. 21:2845-2848 |
| ISSN: | 1466-8033 |
| Popis: | The polymorphic control of the co-crystal carbamazepine–saccharin (CBZ–SAC) metastable form II was achieved by nano-droplet confinement in tandem with droplet surface charging induced by electrospraying the precursor solution. Polymorphic exclusivity is independent of solvent selection. CBZ–SAC co-crystals obtained by electrospraying are compared with supercritical CO2 nano spray-drying, conventional spray-drying and solvent evaporation methods. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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