One-Pot Three Component Domino Reaction for the Synthesis of Novel Isoxazolo[2,3-c][1,3,5]Thiadiazepin-2-Ones Catalyzed by PTSA—A Green Chemistry Approach

Autor: Kundur Govardhan Reddy, P. Venkateshwarlu, Eligeti Rajanarendar, Kammari Thirupathaiah, Saini Rama Krishna
Rok vydání: 2015
Předmět:
Zdroj: Green and Sustainable Chemistry. :107-114
ISSN: 2160-696X
2160-6951
DOI: 10.4236/gsc.2015.53014
Popis: The synthesis of novel isoxazolo[2,3-c][1,3,5]thiadiazepin-2-ones has been achieved in excellent yields by one-pot three-component Domino reaction without the production of toxic waste products by using p-toluene sulfonic acid (PTSA) as a Lewis acid catalyst. PTSA plays a crucial role in the success of the reaction, as well as for increasing reaction rate.
Databáze: OpenAIRE