BRINE SHRIMP TERATOGENIC SCREENING TEST ON SOME SELECTED PLANTS
Autor: | Ayda T Yusuf, Irda Fidrianny, Andreanus Andaja Soemardji, Meti Widiya Lestari |
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Rok vydání: | 2017 |
Předmět: | |
Zdroj: | Asian Journal of Pharmaceutical and Clinical Research. 10:96 |
ISSN: | 2455-3891 0974-2441 |
DOI: | 10.22159/ajpcr.2017.v10i8.18861 |
Popis: | Objectives: The aims of this research were to analyze teratogenic properties on some selected plants which often used for woman’s health were pomegranate ( Punica granatum L.) pericarp, coriander ( Coriandrum sativum L.) seeds, liman ( Elephantopus scaber L.) leaves, fennel ( Foeniculum vulgare M.) seeds, and kaempferia ( Kaempferia galanga L.) rhizomes using brine shrimp teratogenic screening test (BSTST) method. Methods : Artemia cysts were hatched into first stage nauplii then taken and put into seawater medium which contain test substance and kept alive until the second stage, third stage, and fourth stage and then observed number of deaths, morphological abnormalities, body length, and retarded of development for each stage. Results: Hatchability of cysts in fennel seeds compared extracts 1 and 0.5 mg/ml, coriander seeds extract 1 mg/ml, pomegranate rinds extract 6 mg/ml, and liman leaves extracts 6, 3, and 1.5 mg/ml were significantly different to control (p |
Databáze: | OpenAIRE |
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