Vibrational Study of a Nucleoside Analogue with Antitumoral and Antiviral Activity, 5-Fluoro-2′-deoxyuridine, FdU

Autor:	R. Navarro, Lorna E. Bailey, Antonio Hernanz
Rok vydání:	1997
Předmět:	chemistry.chemical_compound chemistry Nucleoside analogue Stereochemistry Computational chemistry Genetics medicine Molecular orbital Biochemistry Deoxyuridine medicine.drug Vibrational spectra
Zdroj:	Nucleosides and Nucleotides. 16:1041-1044
ISSN:	0732-8311
DOI:	10.1080/07328319708006128
Popis:	The advantages of different methods for obtaining a reliable assignment of the vibrational spectra of the antitumoral and antiviral nucleoside analogue, 5-fluoro-2′-deoxyuridine. FdU, are evaluated as a basis for the study of FdU-containing polymers and drug-target interactions. The experimental FT-IR and FT-Raman spectra, are compared with theoretical frequencies obtained by a classical mechanics method and a semiempirical molecular orbital (MO) method, PM3.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::09e025b373fcbc9ec75d6ac74ad29003 https://doi.org/10.1080/07328319708006128 Zobrazit plný text záznamu