Towards Novel HIV-1 Serodiagnostic Tests without Vaccine-Induced Seroreactivity

Autor: Ole Lagatie, Dax Lauwers, Harvinder Singh, Fien Vanroye, Daniel J. Stieh, Johan Vingerhoets, Ludo Lavreys, Valérie Oriol-Mathieu, Will Colón, Chris Verhofstede, Koen Vercauteren, Dorien Van den Bossche, Maria Grazia Pau
Rok vydání: 2023
Předmět:
Zdroj: Microbiology Spectrum.
ISSN: 2165-0497
DOI: 10.1128/spectrum.00715-23
Popis: While the detection of HIV infection is accomplished by several methods, the most common are serological tests that detect host antibodies produced in response to viral infection. However, the use of current serological tests may present a significant challenge to the adoption of an HIV vaccine in the future because the antibodies to HIV antigens detected in currently available tests also tend to be included as antigens in the HIV vaccines in development.
Databáze: OpenAIRE