An Inverse Relationship Between Alcohol and Heroin Use in Heroin Users Post Detoxification
| Autor: | William M. U. Daniels, Ugasvaree Subramaney, Nirvana Morgan |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
050101 languages & linguistics
medicine.medical_specialty 010504 meteorology & atmospheric sciences biology business.industry media_common.quotation_subject 05 social sciences Repeated measures design Abstinence biology.organism_classification 01 natural sciences Gee Heroin Internal medicine Detoxification Cohort medicine 0501 psychology and cognitive sciences Cannabis business Prospective cohort study 0105 earth and related environmental sciences medicine.drug media_common |
| Zdroj: | Substance Abuse and Rehabilitation. 11:1-8 |
| ISSN: | 1179-8467 |
| DOI: | 10.2147/sar.s228224 |
| Popis: | Background Given that fewer than 50% of countries provide Opioid Agonist Maintenance Therapies (OAMT), it is important to assess whether other substances act as a substitute for heroin in recovering heroin users who receive detoxification models of treatment. There is a dearth of prospective studies from low-and-middle-income countries evaluating these patterns of substance use. Methods 300 heroin users from the Gauteng province of South Africa were assessed on entry into inpatient detoxification and then followed-up 3 and 9 months after leaving treatment. Treatment consisted of 1 week of detoxification followed by 6-8 weeks of psychosocial therapy. We measured the overall changes in the prevalence of heroin, alcohol and other drug use at baseline and postrehabilitation. Comparison of these outcomes at enrolment, 3 months and 9 months was performed by a Generalised Estimating Equation (GEE) with the outcome as the dependent variable, observation point as the independent variable, and participant as the repeated measure. Injecting status and treatment completion were included as covariates. We also measured the individual pathways between heroin and alcohol use in the 210 participants that were seen at all three timepoints. Results Of the original cohort, 252 (84.0%) were re-interviewed at 3 months and 225 (75.0%) at 9 months. From baseline to 3 months, the proportion of past month heroin users decreased significantly to 65.5%; however, during this time, the proportion of past month alcohol users increased from 16.3% to 55.2% (p |
| Databáze: | OpenAIRE |
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