The role of intracellular Ca2+ pool in sodium nitroprusside-induced relaxation of rat aorta smooth muscle cells
Autor: | Medvedev Ma, Leonid V. Kapilevich, Panov Aa, I. V. Kovalev, A. G. Popov, Baskakov Mb |
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Rok vydání: | 1999 |
Předmět: |
Aorta
Chemistry Sodium chemistry.chemical_element General Medicine General Biochemistry Genetics and Molecular Biology Sucrose gap Cell membrane medicine.anatomical_structure Biochemistry Permeability (electromagnetism) medicine.artery medicine Biophysics Repolarization Sodium nitroprusside Intracellular medicine.drug |
Zdroj: | Bulletin of Experimental Biology and Medicine. 127:160-162 |
ISSN: | 1573-8221 0007-4888 |
Popis: | A relaxation effect of sodium nitroprusside on smooth muscle cells of rat aorta due to intracellular Ca2+-store refilling is demonstrated using the double sucrose gap technique. It is suggested that sodium nitroprusside-induced repolarization of the smooth muscle cell membrane is associated with inhibition of Ca permeability and/or Ca-dependent K+ permeability of the plasma membrane. |
Databáze: | OpenAIRE |
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