ChemInform Abstract: Remarkable Reaction Rate and Excellent Enantioselective Direct α-Amination of Aldehydes with Azodicarboxylates Catalyzed by Pyrrolidinylcamphor-Derived Organocatalysts

Autor:	Kwunmin Chen, Pang Min Liu, Ying Fang Ting, Hsuan‐Hao Kuan, Raju Jannapu Reddy, Chihliang Chang
Rok vydání:	2010
Předmět:	Reaction rate Chemistry Organocatalysis Enantioselective synthesis Triazole derivatives Organic chemistry General Medicine Amination Catalysis
Zdroj:	ChemInform. 41
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.201018028
Popis:	Remarkable reaction rate and excellent enantioselective direct α-amination of unmodified aldehydes with various azodicarboxylates was catalyzed by pyrrolidinylcamphor organo-catalyst 2a (5 mol-%) to provide the desired aminated products with excellent chemical yields and high to excellent levels of enantioselectivity (up to >99%ee) at 0 °C in CH 2 Cl 2 .
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::09a402c5e847fdbb3a8f0b90ed658897 https://doi.org/10.1002/chin.201018028 Zobrazit plný text záznamu Plný text