Wpływ zakażenia cytomegalowirusem na stan słuchu u dzieci

Autor: Dorota Sułat-Syncerek, Jolanta Sobolewska-Dryjańska, Wiesław Konopka, Małgorzata Śmiechura, Tomasz Gęsicki, Teresa Woźniakowska-Gęsicka
Rok vydání: 2013
Předmět:
Zdroj: Pediatria Polska. 88:159-163
ISSN: 0031-3939
DOI: 10.1016/j.pepo.2013.01.003
Popis: Introduction Hearing loss is a frequent complication of congenital infection with cytomegalovirus (CMV), present in approximately 10–15%, and about 30–60% of all infected, and children with symptomatic form of infection, respectively. Hypoacusis in the course of congenital CMV infection may be uni-, and bilateral, with symptoms occurring immediately after birth, or in the first year of living. The degree of hearing loss is various, ranging from medium to severe, with impairment in high frequencies, its course being variable or gradually worsening. The aim of the study was evaluation of hearing among children with cytomegalovirus infection. Materials and methods The study involved a group of 25 children with cytomegalovirus infection diagnosed by serologic tests and PCR analysis of viral genetic material in blood and urine. In 18 and 7 children, congenital and acquired CMV infection was diagnosed, respectively. All children underwent pediatric and laryngological examination aimed at excluding any abnormalities involving ears, nose, pharynx. Audiometric evaluation consisted on pure-tone threshold audiometry, ABR (Auditory Brainstem Response), transiently evoked otoacoustic emissions (TEOAE) and impedance audiometry. Results In 10 children with congenital CMV infection bilateral, diagnosed bilateral sensorineural hearing loss were diagnosed. There were children with retarded psychomotor development, lesions in central nervous system (CNS). In 5 children there was no hearing impairment in spite of CMV infection symptoms from other organs. In all children with CMV infection acquired after birth the hearing was normal. Conclusions The congenital CMV infection affects hearing negatively. Audiological care is recommended in all children with congenital and acquired cytomegalovirus infection until the end of speech development period, since hearing loss may also occur in asymptomatic infection (congenital and acquired).
Databáze: OpenAIRE