Synthesis, Characterization and Antimicrobial Activity of Metal Complexes of N-(4-methoxybenzylidene) Isonicotinohydrazone Schiff Base

Autor: Md. Sajjad Hossain, Md. Masuqul Haque, Laila Arjuman Banu, Md. Kudrat-E-Zahan, Nayon Uddin, Farzana Khanm Camellia
Rok vydání: 2019
Předmět:
Zdroj: Asian Journal of Chemical Sciences. :1-8
ISSN: 2456-7795
DOI: 10.9734/ajocs/2019/v6i118987
Popis: Two complexes of Cu(II) and Ni(II) with the ligand N- (4-methoxybenzylidene) isonicotinohydrazide, having the formula [M(La)2]2+ (M = Cu(II) and Ni(II)) were synthesized. The ligand was synthesized by the condensation of isonicotinic acid hydrazide (isoniazid) with 4- methoxybenzaldehyde (p- anisaldehyde). The complexes were characterized by FTIR, UV-Vis spectroscopy, molar conductivity, magnetic susceptibility and evaluated for their in vitro antibacterial activity against human pathogens like gram negative Escherichia coli (E. coli) and gram positive Bacillus cereus (B. cereus)strains. The results indicate that all complexes consist of N and O coordination with metals has better antimicrobial activity.
Databáze: OpenAIRE