Fast TiO2-catalyzed direct amidation of neat carboxylic acids under mild dielectric heating

Autor:	Matheus A.G. Nunes, Lucas Schmidt, Chiara Deiana, Erico M.M. Flores, Yuriy Sakhno, Gianmario Martra, Giancarlo Cravotto, E. Calcio Gaudino, Diego Carnaroglio
Rok vydání:	2014
Předmět:	Chemistry Dielectric heating Microwave irradiation Peptide bond Organic chemistry Catalysis
Zdroj:	Catal. Sci. Technol.. 4:1395-1399
ISSN:	2044-4761 2044-4753
DOI:	10.1039/c4cy00038b
Popis:	The development of green protocols for amide bond formation is a major socioeconomic goal for chemical and pharmaceutical industries and an important challenge for academic research. We herein report a protocol for the quantitative conversion of carboxylic acids and amines to form amides at 100 °C in the presence of a TiO2 powder catalyst, under monomodal microwave irradiation. The sustainability of the process appears to be augmented by the ease with which the catalyst is recycled.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::09642566905c0ee5f3ba9fe06c5a59ec https://doi.org/10.1039/c4cy00038b Zobrazit plný text záznamu