Liver metabolomic characterization of Sophora flavescens alcohol extract-induced hepatotoxicity in rats through UPLC/LTQ-Orbitrap mass spectrometry
| Autor: | Yancai Sun, Nengneng Cheng, Peng Jiang |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Pharmacology
Sophora flavescens biology Chemistry Health Toxicology and Mutagenesis Alcohol General Medicine Toxicology Mass spectrometry Orbitrap biology.organism_classification 030226 pharmacology & pharmacy Biochemistry High-performance liquid chromatography law.invention 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Metabolomics law 030220 oncology & carcinogenesis Liver tissue |
| Zdroj: | Xenobiotica. 50:670-676 |
| ISSN: | 1366-5928 0049-8254 |
| DOI: | 10.1080/00498254.2019.1687962 |
| Popis: | This study aimed to observe the influence of Sophora flavescens alcohol extract (SFAE) on hepatic metabolic profiling in rats to explore the possible mechanism of hepatotoxicity induced by S. flave... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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