Evaluation of Biological Effects of Nanosystems of Directed Transport in Experiments in Vivo and Their Application Possibilities in Anti-Tumor Therapy

Autor:	L. A. Naleskina, Lukianova Ny, Liudmila Z. Polishchuk, Demash Dv, Igor M. Todor, Vasyl F. Chekhun
Rok vydání:	2013
Předmět:	Antitumor activity Cisplatin Materials science In vivo Carcinoma medicine Cancer research Nanotechnology General Medicine medicine.disease Transport system medicine.drug
Zdroj:	Advances in Nanoparticles. :145-153
ISSN:	2169-0529 2169-0510
DOI:	10.4236/anp.2013.22023
Popis:	The aim of the investigations was to evaluate benefits of the directed transport system - a nanocomposite, based on cisplatin and magnetite combined with local action of constant magnetic field on the tumor, in experiments in vivo in animals with transplantable Guerin carcinoma. Animals were divided into 5 groups according to the type of agent. We showed that nanocomposite in combination with static magnetic field exercises more prominent anti-tumor activity than cisplatin alone. It should be noted that regardless of the therapeutic agent, in Guerin carcinoma we observed
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0959d38b5a7b78322b7491e808ec44c4 https://doi.org/10.4236/anp.2013.22023 Zobrazit plný text záznamu