| Popis: |
In order to study the mechanisms of brain edema formation and to develop novel therapeutic strategies for patients suffering from intracranial hypertension, it is essential to be able to accurately determine the type of brain edema and to quantify its extent and spatial distribution in clinically relevant animal models in vivo. Modern in vivo imaging techniques, such as magnetic resonance imaging which are reviewed in the previous chapter of this book, are able to visualize brain water content and diffusion; however, the direct determination of the type of brain edema and its precise quantification are still the domain of experimental techniques. The aim of the current chapter is to review the available laboratory techniques for the determination of brain edema and to discuss their usability and reliability. |
