Increased Immunoreactive Erythropoietin in Serum and Kidney Extracts of Rats With Ni 3 S 2 -Induced Erythrocytossis

Autor:	F.W. Sunderman, E. Goldwasser, S.M. Hopfer, M.C. Reid
Rok vydání:	1984
Předmět:	Kidney medicine.medical_specialty business.industry Urology Radioimmunoassay Peptide hormone medicine.anatomical_structure Endocrinology Blood serum Erythropoietin In vivo Internal medicine Toxicity Medicine Erythropoiesis business medicine.drug
Zdroj:	Journal of Urology. 132:629-629
ISSN:	1527-3792 0022-5347
Popis:	Radioimmunoassay of erythropoietin (epo) was performed upon serum samples and kidney extracts from rats that received intrarenal injections of nickel subsulfide (Ni/sub 3/S/sub 2/, 20 mg/rat). Serum epo concentrations were significantly increased from 1 to 4 weeks after Ni/sub 3/S/sub 2/ injection; the highest values occurred at 3 weeks, when serum epo in 5 Ni/sub 3/S/sub 2/-treated rats averaged 230 mU/ml (range = 94 - 370 mU/ml); for comparison, serum epo in 21 vehicle-treated controls averaged 19 mU/ml (range =
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::092fee0343bc01a6b608a94cea6485b8 https://doi.org/10.1016/s0022-5347(17)49799-0 Zobrazit plný text záznamu