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Department of Mathematics and Natural Sciences, College of Sciences and Human Studies, Prince Mohammad Bin Fahd University, Al Khobar 31952, KSA Department of Chemistry and Chemical Biology, Stevens Institute of Technology, Hoboken, New Jersey 07030, USA Department of Mathematics and Natural Sciences, College of Sciences and Human Studies, Deanship of Research, Prince Mohammad Bin Fahd University, Al Khobar 31952, KSA E-mail: adas@pmu.edu.sa, bimalbanik10@gmail.com, bbanik@pmu.edu.sa Manuscript received online 30 December 2019, revised 24 February 2020, accepted 22 May 2020 In this work we have investigated stereoselective synthesis of cis and/or trans ��-lactams under diverse conditions. Ten different reaction conditions have been used for this study. It is important to note that the stereochemistry of the ��-lactam formation reaction depends on the conditions of the experiments, structures of the imines and acid chlorides, order of addition of the reagents, reaction temperature and solvents. To summarize the results, mathematical graphs are plotted. |
