Low Dose Oral and Transdermal Application of Clonidine in Mild Hypertension: Hemodynamic and Biochemical Correlates

Autor:	H. Finster, A. Overlack, K. O. Stumpe, H. M. Müller, R. Kolloch
Rok vydání:	1985
Předmět:	business.industry Sedation Low dose Hemodynamics Pharmacology Plasma renin activity Clonidine Reduced salivation Close relationship Anesthesia medicine medicine.symptom business Transdermal medicine.drug
Zdroj:	Low Dose Oral and Transdermal Therapy of Hypertension ISBN: 9783642537875
DOI:	10.1007/978-3-642-53785-1_14
Popis:	The antihypertensive effect of clonidine has been demonstrated in all grades of hypertension in numerous studies (4, 6, 12, 22, 25, 26). Data on the dose-response relationship for clonidine are only available for the range from 0.300 to 0.750 mg/day (8, 10, 17). In this range, also described as a therapeutic window, there is a close relationship between the hypotensive effect and an increase of the side effects such as sedation and reduced salivation (8, 12, 17).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::090b0a74ff5a314e37012fe4871b27f5 https://doi.org/10.1007/978-3-642-53785-1_14 Zobrazit plný text záznamu