Prise en charge du canal artériel du prématuré : une approche factuelle
| Autor: | V. Gournay |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
congenital
hereditary and neonatal diseases and abnormalities Pediatrics medicine.medical_specialty Evidence-based practice Systemic blood business.industry Mortality rate Gestational age Hemodynamics Evidence-based medicine Natural history 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 030225 pediatrics Ductus arteriosus embryonic structures Pediatrics Perinatology and Child Health cardiovascular system Medicine cardiovascular diseases 030212 general & internal medicine business |
| Zdroj: | Archives de Pédiatrie. 24:175-179 |
| ISSN: | 0929-693X |
| Popis: | A patent ductus arteriosus, very common in the preterm infant (incidence up to 70% in infants less than 28 weeks gestational age), causes a left-to-right shunt leading to overload of the pulmonary circulation and low systemic blood flow. These hemodynamic anomalies are associated with a higher incidence of respiratory, neurological, and digestive complications of prematurity, as well as a higher mortality rate. Although growing knowledge about the natural history, the pathophysiology, and the mechanisms of closure of the ductus arteriosus has resulted in therapeutic progress, management of the patent ductus arteriosus in the preterm infant is still a subject of intense controversy. We describe here the different treatment modalities, their benefits and side effects, and the therapeutic strategies that have been tested in the last four decades. Based on this evidence, the current trend is a personalized approach to the patent ductus arteriosus, adapted to each preterm infant's individual characteristics and risk factors. |
| Databáze: | OpenAIRE |
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