Practical syntheses of antiviral nucleosides

Autor:	Hiroshi Shiragami, Kunisuke Izawa
Rok vydání:	1998
Předmět:	Ganciclovir General Chemical Engineering Industrial scale Stavudine Guanosine Famciclovir General Chemistry Combinatorial chemistry chemistry.chemical_compound chemistry Biochemistry Penciclovir medicine Fermentation medicine.drug
Zdroj:	Pure and Applied Chemistry. 70:313-318
ISSN:	1365-3075 0033-4545
DOI:	10.1351/pac199870020313
Popis:	Guanosine produced by fermentation is one of the nucleosides most readily available on an industrial scale. We have recently developed several processes leading to known antiviral agents starting with guanosine. The processes involve enzymatic transglycosylation for stavudine (d4T), chemical transpurination for acyclovir and ganciclovir, and novel alkylauon for penciclovir and famciclovir.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::08eb679da64f2c4da842fbaf824fdc37 https://doi.org/10.1351/pac199870020313 Zobrazit plný text záznamu