Unstable Angina and Non-ST Elevation Acute Coronary Syndrome Epidemiology and Current Management in Japan (Japan Multicenter Investigation for Cardiovascular Disease-D (JMIC-D) Committee)
Autor: | Kazuhisa Kodama, Hiroshi Nonogi, Saichi Hosoda, Atsushi Hirayama, Chuichi Kawai, Yoshiki Yui, Kazuo Kimura |
---|---|
Rok vydání: | 2007 |
Předmět: |
medicine.medical_specialty
Acute coronary syndrome Unstable angina business.industry ST elevation Incidence (epidemiology) General Medicine medicine.disease Angina Internal medicine Epidemiology medicine Cardiology Cumulative incidence cardiovascular diseases Myocardial infarction Cardiology and Cardiovascular Medicine business |
Zdroj: | Circulation Journal. 71:1335-1347 |
ISSN: | 1347-4820 1346-9843 |
Popis: | Background A multicenter study was conducted to assess the current medical management of unstable angina (UA) and non-ST-elevation acute coronary syndrome in Japan. Methods and Results This study presents the results of a nationwide questionnaire survey of 770 sites and a case report investigation performed at 20 sites. The questionnaire survey revealed that the number of acute myocardial infarction (AMI) patients treated annually was 1.56-fold greater than the number of UA patients. Non-ST-elevation AMI accounted for 17% of all patients with AMI. Analysis of case reports for 885 UA patients showed extensive use of invasive treatment. In the UA patients, the cumulative incidence of a composite endpoint (all-cause mortality, AMI, and urgent coronary revascularization) was 2% at 1 month and 9% at 6 months. Stratified analysis with respect to the composite endpoint through 6 months showed a significantly lower incidence in patients treated with a calcium-channel blocker than in patients not treated with a calcium-channel blocker. Conclusions In Japan, fewer patients are hospitalized annually for treatment of UA than for AMI. The largest percentage of UA patients had Braunwald class III disease. Non-ST-elevation AMI is managed in Japan according to the principle of early invasive treatment, resembling the treatment for ST-elevation AMI. The outcome of treatment is better for Japanese UA patients than for Japanese AMI patients. (Circ J 2007; 71: 1335 - 1347) |
Databáze: | OpenAIRE |
Externí odkaz: |